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'Intelligent' Materials To Revolutionise Surgical Implants - Nanotechnology Will Provide Superior Implants For Orthopaedic Patients
A brand new process that could revolutionise the reliability and
durability of surgical implants, such as hip and knee replacements, has
today, 2 December 08, received recognition for its medical and commercial
potential by achieving one of the world's most sought after accolades.  A
team of researchers, led by the Science and Technology Facilities Council
(STFC), has received a Medical Futures Innovation Award for its high
technology process designed to coat surgical implants with fibres that,
for the first time, will encourage the implant to 'bond' with living bone
and to last the lifetime of the patient.
This unique surface engineering process is being developed at the
Micro-Nano Technology Centre (MNTC) at STFC. In collaboration with the
Electrospinning Company Ltd (TECL) and Anglia Ruskin University, the
concept will be taken forward under the guidance of a Medical Futures
team, and eventually exclusively licensed to TECL, a spin out company of
STFC.
This advanced nanotechnology technique builds on an existing technique
known as electrospinning, and will utilise a vastly superior
electrospinning source to create bespoke fibrous materials.
Electrospinning is a process that uses an electrical charge to turn
polymers into extremely thin fibres that are 'spun' to form a mat of fine
fibres. It is seen as a platform technology for the medical sector with a
wide range of applications including tissue regeneration and drug
delivery. The MNTC has developed systems to increase the production rate
of nanofibres which has been previously prevented this technology from
being adopted by industry.
In this case, nanosized hair- like structures, a thousand times thinner
than the width of a human hair, are electrospun at MNTC and added to the
surface of an orthopaedic implant to create a 'living interface' between
the artificial implants and living bone. Not only does this improve the
performance of the implants it also significantly increases their
durability to last the lifetime of the patient. Any stress on the implant
is relieved, making it more reliable and durable. Additionally, it is
also possible to add a unique biological coating that can facilitate
growth and improve the bonding of healthy tissue to the implant, primarily
benefitting patients with osteoarthritis in the aging population and
sports injuries in the younger population.
This process will be transferred to UK industry and TECL will provide
access to state-of-the-art electrospinning systems. TECL has spun out from
STFC to provide open access to electrospinning equipments and expertise to
organisations that would like to explore the technique's potential. The
main benefit is that this can be done without commercial companies
committing to capital investment or developing in-house expertise until
the potential value of electrospinning to the organisation is fully
understood. TECL is based both at the Daresbury Science and Innovation
Centre in Cheshire and at STFC's Rutherford Appleton Laboratory in
Oxfordshire, and was founded by CLIK, the wholly-owned technology
exploitation company of STFC. TECL's specialised facilities are designed
to extend current electrospinning capabilities so that nanofibres can be
reproduced in volume.
Dr Robert Stevens, Head of the MNTC at STFC said: "This award provides a
major step forward for the future of patients requiring surgical implants
and I am thrilled that this concept was selected as an award winner over
several hundred entries. Our award is given for translational research
innovation to meet the current and future orthopaedic needs of patients."
Mansel Williams, Chief Executive of The Electrospinning Company said: "Ten
percent of patients receiving surgical implants go on to develop infection
and loosening of their implants, costing the UK at least £14 million every
year, £224 million globally. We want to eliminate this by creating the
ideal implant surface matched to the individual patient, benefitting both
the patient and the economy. This award will now allow us to scale up the
testing and commercialisation of these implants"
The Medical Futures Innovation Awards, which were announced at the Medical
Futures Innovators Gallery in London, are one of the UK's most highly
coveted medical awards, rewarding ground-breaking innovation from front
line clinicians and scientists with ideas that have the potential to
transform peoples' lives and demonstrate the UK's position as a world
beater.
About the Electrospinning Company
The Electrospinning Company Ltd is a spin-out from the Science and
Technology Facilities Council (STFC) and received initial funding from
The Rainbow Seed Fund
Electrospinning has the unique ability to produce nanofibres of different
materials. Almost any soluble polymer with sufficiently high molecular
weight can be electrospun. Nanofibres made of natural polymers, polymer
blends, nanoparticle or drug impregnated polymers have been successfully
demonstrated.
Electrospinning equipment and expertise are available for research into
conventional nanofibre-related applications. In addition, The
Electrospinning Co Ltd is developing MEMs-based electrospinning nozzle
arrays and scale up systems.
These innovations are designed to extend current electrospinning
capabilities so that novel nanofibre platforms can be reproducibly made in
volume. This provision is expected to improve existing nanofibre solutions
and also create new application opportunities.
Operating on a commercial basis as a NanoCentral associate, The
Electrospinning Co Ltd offers access to electrospinning equipment and
expertise to organisations that would like to explore the technique's
potential in their specific applications. The main benefit is that this
can be done without committing to capital investment and building up
in-house expertise until the potential value of electrospinning to the
organisation is fully understood.
There are also benefits to experienced organisations that have
electrospinning and nanofibre expertise but would like to collaborate with
The Electrospinning Co Ltd to develop specific applications to prototype
stage. These include application specific equipment design and
engineering, electrospinning raw materials and process development.
Science and Technology Facilities Council
The Science and Technology Facilities Council ensures the UK retains its
leading place on the world stage by delivering world-class science;
accessing and hosting international facilities; developing innovative
technologies; and increasing the socio-economic impact of its research
through effective knowledge exchange partnerships.
The Council has a broad science portfolio including Astronomy, Particle
Physics, Particle Astrophysics, Nuclear Physics, Space Science,
Synchrotron Radiation, Neutron Sources and High Power Lasers. In addition
the Council manages and operates three internationally renowned
laboratories:
-Â Â Â Â Â Â Â The Rutherford Appleton Laboratory, Oxfordshire
-Â Â Â Â Â Â Â The Daresbury Laboratory, Cheshire
-Â Â Â Â Â Â Â The UK Astronomy Technology Centre, Edinburgh
The Council gives researchers access to world-class facilities and funds
the UK membership of international bodies such as the European Laboratory
for Particle Physics (CERN), the Institute Laue Langevin (ILL), European
Synchrotron Radiation Facility (ESRF), the European organisation for
Astronomical Research in the Southern Hemisphere (ESO) and the European
Space Agency (ESA). It also contributes money for the UK telescopes
overseas on La Palma, Hawaii, Australia and in Chile, and the MERLIN/VLBI
National Facility, which includes the Lovell Telescope at Jodrell Bank
Observatory.
The Council distributes public money from the Government to support
scientific research. Between 2008 and 2009 we will invest approximately
£787 million.
The Council is a partner in the UK space programme, coordinated by the
British National Space Centre.
About CLIK
Central Laboratory Innovation and Knowledge Transfer Limited ('CLIK') is
the wholly-owned technology exploitation company of the Science &
Technology Facilities Council. CLIK has the exclusive rights to the
commercial exploitation of STFC's intellectual property at Rutherford
Appleton Laboratory (RAL) in Oxfordshire, the Daresbury Laboratory (DL) in
Cheshire and the Astronomy Technology Centre (ATC) in Edinburgh. Working
closely with the technical inventors, the CLIK team progresses individual
projects through various business models to the point of implementation as
commercial licenses or spin-out companies.
Science and Technology Facilities Council
"Inteligente" Materiale Pentru a Revolutionise trusa implante - Nanotehnologia va oferi Superior implanturi ortopedice Pentru Pacienþii - 'Intelligent' Materials To Revolutionise Surgical Implants - Nanotechnology Will Provide Superior Implants For Orthopaedic Patients - articole medicale engleza - startsanatate