Relaxin Expression By Adenovirus Improves Anticancer Activity
Chae-Ok Yun, Ph.D., of the Yonsei University College of Medicine in Seoul, Korea, and colleagues inserted a gene called relaxin, which is structurally similar to insulin, into adenoviruses and then assessed its expression and action against cancers in mice. They found that adenoviruses expressing relaxin spread to more cancer cells and penetrated deeper into tumors than the unmodified viruses alone. The relaxin adenovirus also inhibited tumor growth and metastasis and helped mice survive longer.
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Article adapted by Start Sanatate from original press release.
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Other highlights in the October 18 JNCI
Contact: Chae-Ok Yun
Note: The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute. Attribution to the Journal of the National Cancer Institute is requested in all news coverage. Visit the Journal online at http://jncicancerspectrum.oxfordjournals.org/.
Contact: Ariel Whitworth
Journal of the National Cancer Institute
Exprimarea Relaxin Prin Adenovirus Îmbunãtãþeºte Anticancer de activitate - Relaxin Expression By Adenovirus Improves Anticancer Activity - articole medicale engleza - startsanatate