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17,500 Participants Needed To Enroll In Major Colorectal Cancer Clinical Trials
The Coalition of Cancer Cooperative
Groups (Coalition) announced today the launch of QuickLink -- a
new resource designed to help patients, caregivers and people at risk learn
more about major colorectal cancer clinical trials. QuickLink can be found by
visiting www.CancerTrialsHelp.org.
"The only way to move toward a cure for colon cancer is through research,"
said Robert L. Comis, MD, president, Coalition of Cancer Cooperative Groups.
"As a direct outcome from clinical trials, five new drugs have received FDA
approval over the last five years making new and better treatments more
available to patients with colorectal cancer today than ever before. "
Patients who join cancer clinical trials are given the best available
treatment or a new treatment that, based on early clinical data, could be an
improvement over the current standard therapy. In addition, there are many
trials available for prevention, screening and early detection of colorectal
cancer or pre-cancerous polyps.
"Clinical trials are not just a vital source of information, they can be
of great value to the individuals who participate in them," said Dr. Comis.
"A common misperception that some patients receive placebo has prevented some
people from participating in clinical trials." Placebos (also called "sugar
pills") are rarely used in cancer clinical trials and are never used in place
of treatment.
There are nearly 270 colorectal cancer studies currently available for
patients in the U.S., out of over 4,500 cancer trials of all types.(1) Now,
QuickLink provides information on ten of the largest colorectal trials
currently available, along with links to patient support services and quick
access to the screening capabilities of TrialCheck(R), the Coalition's
signature database and navigator of thousands of cancer clinical trials.
TrialCheck offers a fast and easy way for people to locate clinical trials.
Results are displayed by proximity to the user's Zip Code. It is the most
frequently updated searchable database of cancer clinical trials in the U.S.
"Unfortunately, less than five percent of people diagnosed with cancer
will be treated through enrollment in a clinical trial," said Kevin Lewis,
Chairman of the Board, Colon Cancer Alliance. "Our organization is very
supportive of the Coalition and its efforts to accelerate research. We
believe that in recent years patients have received better treatment options
in trials, and if we can educate people about clinical trials I am confident
that we can increase enrollment in these high-priority colon cancer trials."
Focus Efforts, Accelerate Results
Recently a group of experts from the oncology research community,
academia, cancer cooperative groups, patient advocacy and industry identified
ten trials as high priority colorectal clinical studies that address important
research opportunities and merit support for rapid completion. Combined,
these ten large studies will need to enroll more than 17,500 participants.
The Coalition's Scientific Leadership Council in Gastrointestinal Cancer
presented these trials as part of their recommendations for the future
direction of colorectal cancer research at a forum in Washington DC in
December 2005 and at a major GI cancer meeting in San Francisco in January
2006.
In the near term this group will raise awareness about the availability of
these trials. "We are committed to focusing our efforts on helping to complete
enrollment in these ten, pivotal colorectal cancer clinical trials," said
Michael J. O'Connell, MD, Chairman, Scientific Leadership Council in GI
Council. "If we can accelerate the completion of these trials we can move
faster toward more effective diagnosis, prevention, and treatment of colon
cancer."
Excluding skin cancer, colorectal cancer is the third most common cancer
in the United States and Canada (after lung and breast in women, and lung and
prostate in men). The American Cancer Society estimates that there will be
148,610 new cases of colorectal cancer diagnosed in the U.S. in 2006. The ACS
also reports mortality rates from colorectal cancer have declined in both men
and women over the past two decades, at an average of 1.8% per year. This
decrease reflects declining incidence rates and improvements in survival. The
one- and five-year relative survival for persons with colorectal cancer is 83%
and 64%, respectively. Survival continues to decline beyond five years to 58%
at 10 years after diagnosis.(2)
The Coalition of Cancer Cooperative Groups
The Coalition of Cancer Cooperative Groups is a non-profit organization
seeking to increase participation in high-quality cancer clinical trials and
accelerate the development of new cancer therapies. Its membership comprises
all of the nation's federally-funded cancer cooperative groups, representing
nearly 8,000 oncology researchers in 1,700 hospitals and oncology practices
nationwide, along with over 40 patient advocacy organizations.
The Scientific Leadership Council in GI Cancer
The Scientific Leadership Council in GI Cancer is a multidisciplinary
group of professionals representing the spectrum of diagnostic, therapeutic,
and laboratory disciplines engaged in colorectal cancer clinical research.
Members include national research leaders from the areas of diagnostic
radiology, surgery, radiation oncology, medical oncology, novel therapeutics,
correlative laboratory science, biostatistics, clinical trials methodology,
and quality of life research. Representation from cooperative groups,
Specialized Programs of Research Excellence (SPORES), cancer centers, and
leading academic and community institutions ensures that wide ranges of
research perspectives are represented. Its purpose is to recommend and
profile the most promising research in GI cancers, and to bring together
stakeholders in the cancer community to help form common goals and
understanding around these research needs.
(1) http://www.clinicaltrials.gov
(2) American Cancer Society, Cancer Facts & Figures, 2006
Coalition of Cancer Cooperative Groups
http://www.CancerTrialsHelp.org
http://www.clinicaltrials.gov
17500 participanþi necesar pentru a inscrie majore în studiile clinice cu cancer colorectal - 17,500 Participants Needed To Enroll In Major Colorectal Cancer Clinical Trials - articole medicale engleza - startsanatate