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ASCO GU 2008 - Death From Prostate Cancer In A Screened Population: Relation To PSA Levels At First Screen In The ERSPC Section Rotterdam

UroToday.com - Within the ERSPC, men with a PSA 7, (17%) and 53 were potentially non-curable. 8 men have died of disease at 12 years and 7 were interval detected cancers. In the non-curable CaP cases, most had high PSA levels at the followup interval. In those who died of CaP, the PSA at detection was less than 3ng/ml at first screening and rose significantly at the interval detection.

If the PCPT regimen was applied to their study, the detection number would have been 3,472 rather than 700 cases. Calculations show that 299 prostate biopsies would have been necessary to prevent the detection of one non-curable CaP. 1,981 prostate biopsies would have been necessary to prevent one CaP death. Thus, in a setting with repeat screenings, men with low PSA values should not be biopsied. The PSA range 2.0-2.9 should primarily be targeted.

Presented by M. J. Roobol at the American Society of Clinical Oncology (ASCO) - 2008 Genitourinary Cancers Symposium - A Multidisciplinary Approach - February 14-16, 2008 San Francisco, California, USA

Reported by UroToday.com Contributing Editor Christopher P. Evans, MD, FACS Professor & Chairman Department of Urology University of California, Davis, School of Medicine Sacramento, CA

UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice.

To access the latest urology news releases from UroToday, go to: www.urotoday.com

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ASCO gu 2008 - moartea de la un cancer de prostatã în populaþia Ecranat: PSA raport cu nivelurile de la primul ecran în secþiunea ERSPC Rotterdam - ASCO GU 2008 - Death From Prostate Cancer In A Screened Population: Relation To PSA Levels At First Screen In The ERSPC Section Rotterdam - articole medicale engleza - startsanatate