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Consumer behavior in the setting of OTC statin availability
Lessons from the consumer use study of OTC Mevacor -
Despite the proven benefits of statins, large numbers of patients meeting guideline criteria for therapy are not receiving
these drugs.
It has been suggested that over-the-counter (OTC) availability of statins would allow more consumers to use statins and
achieve cardiovascular risk reduction. However, concerns have been raised as to the consumers' ability to self-manage
hyperlipidemia and use statins safely.
The Consumer Use Study of OTC Mevacor (CUSTOM) was designed to define consumer behaviors in the setting of OTC statin
availability. The study was conducted in a simulated OTC setting and allowed consumers to purchase once-daily lovastatin 20
mg. The CUSTOM dataset includes >3,300 consumers who evaluated OTC lovastatin for potential purchase at study sites and
follow-up information on purchasers for up to 6 months of self-managed therapy.
These data have been analyzed to address consumers' knowledge of their cholesterol concentrations as well as their ability to
make OTC use decisions based on their cardiovascular risk, avoid drug-drug interactions, self-manage their cholesterol
treatment after deciding to use the OTC product, and maintain interactions with physicians while using lovastatin OTC.
The results showed that most study participants appropriately self-selected OTC statin therapy and managed their treatment.
Use of OTC statins by consumers needing more intensive statin therapy or facing the risk of potential drug-drug interactions
remains an area of concern but occurred infrequently in CUSTOM.
These data are important for making an informed
risk-benefit decision concerning OTC statin availability.
SOURCE: American Journal of Cardiology 2004 Nov 4; 94(9A): 22F-29F
To contact the principal investigator of the study, Eric Brass, M.D., Ph.D, please call David Feuerherd at 310-215-0234 /
310-222-2820 or e-mail him at df@issuesmanagement.com.
LA BioMed Medical/Research briefs - January 2005
Contact: David Feuerherd
df@issuesmanagement.com
310-215-0234
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA
BioMed)
View drug information on Mevacor.
Comportamentului consumatorilor în cadrul OTC statin disponibilitate - Consumer behavior in the setting of OTC statin availability - articole medicale engleza - startsanatate