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First Genome-Wide Splice Variant Arrays Launched by Jivan Biologics
The first commercial
genome-wide microarrays for alternate splicing were launched
today by Jivan Biologics, Inc., a privately held company.
Manufactured by Agilent Technologies and available as a
catalogue product, Jivan's TransExpress(TM) Whole Spliceome
enables researchers to detect changes in RNA splicing across
the entire human genome for a broad range of clinical and
research applications.
"TransExpress(TM) Whole Spliceome places Jivan at the
forefront of a paradigm shift from gene arrays to splice
variant arrays that will transform the half billion dollar a
year microarray market," said Subha Srinivasan, PhD, CEO and
Founder of Jivan Biologics.
With patent-pending technology for splice variant detection,
TransExpress(TM) Whole Spliceome is the culmination of four
years of research and experimental validation by Jivan
scientists. It has benefited from two SBIR grants from the
National Institutes of Health. Since 2002, several corporate
and academic research collaborations have validated Jivan's
splice array technology.
By differentiating among the splice isoforms of a gene,
TransExpress(TM) Whole Spliceome multiplies the number of
potential clinical biomarkers and molecular diagnostics by a
factor of four or more compared to conventional gene arrays.
TransExpress(TM) Whole Spliceome includes 148,693 probes for
135,706 alternately spliced sites for 98,382 splice isoforms
of 23,484 human genes.
It works with standard hybridization kits and scanners
available from Agilent Technologies and other vendors.
TransExpress(TM) Whole Spliceome can be ordered online at
jivanbio.com.
Jivan Biologics empowers scientists with new insight by
providing a full catalogue of splice variant arrays for drug
development and biological research. Available as a service
since 2001 and as catalogue products since 2003, Jivan's
flagship TransExpress(TM) arrays are the first commercial
microarrays for alternate splicing.
Jonathan Bingham
415-425-4115
Email: jbingham@jivanbio.com
jivanbio.com
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