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New natural extract for treating MRSA
A presentation at the American Society for Microbiology meeting in Atlanta hears today about a safe, natural and
effective treatment for MRSA infections that are multi-drug resistant. The new formulations of capsules, liquid and crème are
extracted from fresh garlic to yield the ONLY commercially available presentation of Allicin. Allicin is an excellent natural
antimicrobial that can deal with a range of drug resistant bacteria.
How does Allicin work?
Stabilised allicin has now been formulated into an
active range of products
called Allimed™. Powdercapsules,
liquid, soap and
cream presentations all
show highly significant
activity against multi-drug
resistant organisms including
MRSA.
The mechanism of action
of allicin may be due to
inhibition of certain thiolcontaining
enzymes in the
microorganisms by the
rapid reaction of thiosulfinates
with thiol groups.
This was assumed to be
the main mechanism involved
in the antibiotic
effect of allicin. Recent
studies have suggested that
the mechanism of action of
Allicin may be its ability
to react with a model thiol
compound (L-cysteine) to
form the S-thiolation
product
S-allylmercaptocysteine.
The identification
of the thiolation product
was proven by nuclear
magnetic resonance as
well as by mass spectroscopy.
The main antimicrobial
effect of allicin is due
to its interaction with important
thiol-containing
enzymes. In the amoeba
parasite, allicin was found
to strongly inhibit the cysteine
proteinases, alcohol
dehydrogenases as well as
the thioredoxin reductases
(Ankri et al., unpublished
results) which are critical
for maintaining the correct
redox state within the
parasite. Inhibition of
these enzymes was observed
at rather low concentrations
(
New natural extras pentru tratarea MRSA - New natural extract for treating MRSA - articole medicale engleza - startsanatate