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News From The American Chemical Society Nov. 12, 2008

A faster test for the food protein that triggers celiac disease

Researchers in Spain and the United Kingdom are reporting development of a faster test for identifying the food protein that triggers celiac disease, a difficult-to-diagnose digestive disease involving the inability to digest protein called gluten that occurs in wheat, oats, rye, and barley. The finding could help millions of people avoid diarrhea, bloating, and other symptoms that occur when they unknowingly eat foods containing gluten. The study is scheduled for the December 15 issue of Analytical Chemistry, a semi-monthly journal.

In the new report, Alex Fragoso, Ciara O'Sullivan and colleagues note that patients with celiac disease can avoid symptoms by avoiding foods that contain gluten. Doing so can be tricky, however, because gluten may be a hidden ingredient in unsuspected foods, such as soy sauce, canned soups, and licorice candy. Some prepared foods list gluten content on package labels, but identifying its presence remains difficult and time-consuming.

The scientists describe development of a new sensor that detects antibodies to the protein gliadin, a component of gluten. Laboratory tests showed that it is superior to the so-called enzyme-linked immunosorbent assay (ELISA), now the standard test for gliadin. It took the new test barely 90 minutes to detect gliadin in the parts per billion range, compared to 8 hours for the ELISA test. Although both tests were equally accurate, the new sensor would be easier to use at food manufacturing plants, the researchers note. - MTS

ARTICLE: "Electrochemical Immunosensor for Detection of Celiac Disease Toxic Gliadin in Foodstuff"

CONTACT:
Alex Fragoso, Ph.D.
Ciara K. O'Sullivan, Ph.D.
Universitat Rovira I Virgli
Tarragona, Spain

"Powerhouses" from living cells power new explosives detector

Researchers in Missouri have borrowed the technology that living cells use to produce energy to develop a tiny, self-powered sensor for rapid detection of hidden explosives. The experimental sensor, about the size of a postage stamp, represents the first of its kind to be powered by mitochondria, the microscopic "powerhouses" that provide energy to living cells, the researchers say. Their study is scheduled for the November 26 issue of the weekly Journal of the American Chemical Society.

In the new study, Shelley Minteer, Marguerite Germain, and Robert Arechederra point out that today's explosives detectors are expensive, bulky, and complex. Society needs smaller, cheaper, simpler detection devices, based on technology that perhaps could be incorporated into cell phones and portable digital music players, the researchers suggest.

The scientists describe development of an experimental sensor built from a special biofuel cell, essentially a battery-like device consisting of a thin layer of mitochondria sandwiched between a carbon-based electrode and a gas-permeable electrode. In laboratory studies using nitrobenzene as a test compound, the sensor showed a significant boost in electrical power in the presence of the substance, demonstrating the sensor's potential for detecting TNT and related explosives, the researchers say. - MTS

ARTICLE: "Nitroaromatic Actuation of Mitochondrial Bioelectrocatalysis for Self-Powered Explosive Sensors"

CONTACT:
Shelley D. Minteer, Ph.D.
Saint Louis University
St. Louis, Missouri 63103

Healthful plant nutrients also found in meat and milk

Counterintuitive as it may seem, those healthful phytoestrogen nutrients that consumers usually associate with fruits and vegetables also exist in foods of animal origin. After all, "phyto" means "plant." Now the first comprehensive study of phytoestrogen content in foods has identified the best sources of these nutrients. The study is scheduled for the November 26 issue of ACS' bi-weekly Journal of Agricultural and Food Chemistry.

In the study, Gunter G. C. Kuhnle, Laure Thomas and colleagues point out that phytoestrogens have garnered increasing attention for their beneficial role in preventing several diseases, including osteoporosis, type-2 diabetes and certain cancers. But much of the scientific research on these compounds has focused on their occurrence in plant-based foods, which has led to an underestimation of actual amounts people consume, the study says.

The researchers analyzed 115 foods of animal origin and found that all food groups studied contained phytoestrogens. Isoflavones - one of the three major classes of these compounds - were considerably higher in soy-based foods. In fact, the amount of phytoestrogens in soy-based infant formula was more than 300 times higher than in normal infant formula. In animal products, phytoestrogens are low when compared to foods containing soy, the paper notes, but the range is similar to that of many commonly consumed vegetables. - JS

ARTICLE: "Phytoestrogen Content of Foods of Animal Origin: Dairy Products, Eggs, Meat, Fish, and Seafood"

CONTACT:
Laure Thomas
MRC Senior Press Officer
Medical Research Council
20 Park Crescent
London, W1B 1AL

Toward greener, more energy-efficient buildings

In the face of growing environmental concerns and a renewed interest in energy efficiency, the construction of homes and businesses that emphasize "green" construction materials is on the rise, according to an article scheduled for the November 17 issue of Chemical & Engineering News, ACS' weekly newsmagazine.

In the two-part C&EN cover story, Senior Business Editor Melody Voith notes that while green building materials were once viewed as a trendy environmental statement focusing on natural or recyclable items, these materials now are emerging as practical, high-performance products that also provide energy efficiency. The market for green building products and services was $12 billion in 2007 and experts project it to increase to $60 billion by 2010, the article notes.

Today, a "green building" usually refers to a commercial building or home that has been certified as such by the U.S. Green Building Council (USGBC) for its use of environmentally-friendly materials, among other considerations. The USGBC plans to release updated certification standards in 2009 that emphasize lower energy use and reduced greenhouse gas emissions, the article notes. The U.S. Department of Energy, meanwhile, assists builders in making homes more energy efficient by publishing guideline specifications for insulation, windows, ductwork, appliances, and other items. Says one producer of construction materials, "All of a sudden, green is becoming serious and growing up. It is a huge shift in how buildings are designed and constructed."

ARTICLE: "High-Performance Buildings"

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Article adapted by Start Sanatate from original press release.
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The American Chemical Society - the world's largest scientific society - is a nonprofit organization chartered by the U.S. Congress and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

Source: Michael Woods
American Chemical Society





Noutati de la American Chemical Society Nov 12, 2008 - News From The American Chemical Society Nov. 12, 2008 - articole medicale engleza - startsanatate