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Skin-Lightening Cremes Sold On Black Market Have Serious Health Risks
A Clinical Picture described in the February 16, 2008 issue of The
Lancet underlines the perils of using skin lightening creams sold on
the black market. Dr. Tricia Tan and Dr. Tony Goldstone of the
Endrocrine Unit in the Department of Investigative Medicine, Imperial
College Healthcare NHS
Trust, Hammersmith
Hospital, London, UK, were involved in the team that treated the
patients and co-authored this piece.
The woman, at 28 years old, had gained 12.7 kg (28.0 lb) in the
previous three years and had been attempting impregnation for 18 months
unsuccessfully, despite a regular menstrual cycle. She also described
stripes on her arms, back abdomen, and legs, in addition to sensitivity
to bruising and recurrent thrush or yeast infection. Otherwise, her
medical background was not remarkable, and she specifically denied the
use of illegal or prescription drugs.
Doctors noted central obesity (a Body Mass Index (BMI) greater than
36.6 kg/m2, where a BMI that is greater than 30
is considered obese), a pad of fat between her shoulder blades, and
round face. She had pigmented stretch marks on her body, as well as
thin, bruised skin, and mild hair growth on her back and face, combined
with muscle weakness.
Tentatively, a diagnosis of Cushing's syndrome was proposed. Cushing's
syndrome results from excess levels of steroid hormones in the blood,
generally coming from the adrenal glands, and is usually caused by a
directly malfunctioning adrenal gland or an overactive signal from the
pituitary gland to the adrenal glands with the same result. However, in
this patient, blood concentrations of cortisol, a steroid hormone, and
corticotropin, the signaling hormone from the pituitary, were very low.
A second inquiry was made to the patient regarding drugs, and the
patient conceded to using a skin-lightening cream for up to seven years
previous. The source of this cream was not a pharmacy but rather a
local shop, which was not stocking it legally. Deeper investigation
made it clear that the cream had clobetasol, a strong steroid,
and that she had been using two tubes (approximately 60g) per week.
A conclusion was made regarding skin-lightening cremes as they impact
the clinical settting.
"Patients are often reluctant to admit that they
have used skin-lightening creams - especially if these are supplied
illegally.
Similarly, doctors can be unaware of the need to inquire. But the
market is worth millions of
pounds a year, in the UK alone. Creams can contain toxic substances,
such as steroids and
hydroxyquinone - and patients are typically unaware of the risks."
The pursuit of beauty
Maralyn Druce, Anthony P Goldstone, Tricia M M Tan, Karim Meeran
The Lancet, February 16, 2008, Volume 371
Click
Here For Full Text
Written by Anna Sophia McKenney
Copyright: Start Sanatate
Not to be reproduced without permission of Start Sanatate
-Piele Cremes Reduceþi vândut pe piaþa neagrã au grave riscuri de sãnãtate - Skin-Lightening Cremes Sold On Black Market Have Serious Health Risks - articole medicale engleza - startsanatate