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Tanabe to Launch AIDS-related "ALIXA Tablets 450 mg"

Tokyo, Japan, Nov 25, 2004 - (JCN Newswire) - As of November 25, 2004, Tanabe Seiyaku Co. Ltd.( President: Natsuki Hayama)is to launch an AIDS-related drug "VALIXA Tablets 450 mg" (Generic Name:Valganciclovir hydrochloride) with indication for treatment of CMV retinitis in AIDS patients.

"VALIXA Tablets 450 mg" is a pro-drug preparation of ganciclovir, which was developed by F. Hoffmann-La Roche AG (Basel, Switzerland). In clinical trials carried out overseas, it has proven to be highly efficacious in treatment of CMV retinitis (both induction treatment and maintenance treatment) in AIDS patients.

CMV retinitis is a syndrome which affects about 20 to 30% of AIDS patients. It is also known to possess a high risk of blindness. Capsules and IV formulation of ganciclovir used to be mainstay treatment but they posed constraint on patients by giving them pill burden of 12 capsule per day or obliging them to be hospitalized for infusion.

"VALIXA Tablets 450 mg" has remarkably improved bioavailability which is approximately ten times as much as that of ganciclovir oral preparation (Denosine Capsule 250) and led to equivalent clinical effects to that of ganciclovir injection. Through these characteristics, this product is believed to contribute much to improved QOL of patients by reducing daily pill burden.

Tanabe Seiyaku Co., Ltd. will make its best efforts to contribute to treatment of CMV retinitis in AIDS patients by collecting and conveying information on appropriate use of "VALIXA Tablets 450 mg" and try to establish undisputed reputation of "ALIXA Tablets 450 mg" as standard treatment for CMV retinitis.

About Tanabe Seiyaku Co., Ltd.

Tanabe Seiyaku Co., Ltd. (TSE: 4508) is a manufacturer and distributor of pharmaceuticals for cardiovascular system, circulatory system, central nervous system, respiratory system and gastrointestinal system, tonics, antibiotics, chemotherapeutics, hormones, vitamins, diagnostic agents and mediums, as well as other products such as food additives and cosmetics. Operations are carried out through various divisions: prescription drugs, OTC drugs, diagnostic agents, animal drugs, chemicals, food additives, and dies/pigments.

Contact:
Tanabe Seiyaku Co., Ltd.
Corporate Communications Division
3-2-10, Doshomachi, Chuo-ku,
Osaka 541-8505, JAPAN
Phone : +81-6-6205-5211,
Fax : +81-6-6205-5105
http://www.tanabe.co.jp
http://www.japancorp.net/Article.Asp?Art_ID=8855





Tanabe a lansa SIDA legate de "ALIXA Tabletele 450 mg" - Tanabe to Launch AIDS-related "ALIXA Tablets 450 mg" - articole medicale engleza - startsanatate