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Bach Model Slightly Underestimates Smokers' 10-Year Lung Cancer Rates In ATBC Study

New data suggest that a lung cancer risk model used to predict a smoker's risk of developing lung cancer underestimates the observed lung cancer risk over a 10-year period.

Kathleen A. Cronin, Ph.D., of the National Cancer Institute in Bethesda, Md., and colleagues examined the ability of a model developed by Peter B. Bach, et al., to predict cancer rates in 6,239 smokers in the in the control group of the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) study. They compared actual rates of cancer to rates predicted by the Bach model for 10 years.

The authors observed that the number of lung cancers predicted by the Bach model was lower than the actual number of lung cancers seen. For example, the underestimation was greater for men who smoked under 20 cigarettes a day. The ability of the model to distinguish between low and high risk smokers was similar to that originally reported and comparable to other cancer risk models. The authors suggest that some of the differences between the model's projections and what was seen in the ATBC study might have been due to routine screening, which would lead to more cancers being discovered.

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Article adapted by Start Sanatate from original press release.
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Highlights from the May 2006 Journal of the National Cancer Institute

Contact: NCI Press Officers

Note: The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute. Attribution to the Journal of the National Cancer Institute is requested in all news coverage. Visit the Journal online at http://jncicancerspectrum.oxfordjournals.org/.

Contact: Ariel Whitworth
Journal of the National Cancer Institute





Model de Bach Slightly subestimeazã fumãtori "de 10 ani Cancerul pulmonar Tarife În Studiul ATBC - Bach Model Slightly Underestimates Smokers' 10-Year Lung Cancer Rates In ATBC Study - articole medicale engleza - startsanatate