Abuse History Affects Pain Regulation In Women With Irritable Bowel Syndrome
Researchers used brain imaging to show that patients with IBS who also had a background of abuse were not as able to turn off a pain modulation mechanism in the brain as effectively as were IBS patients who had not suffered abuse.
IMPACT:
According to previous studies, a significant percentage of patients with IBS have been physically or sexually abused at some time in their lives. The new finding may help explain why those in this subset of IBS patients experience greater pain and poorer health outcomes than others with the disorder. Such insight provides a greater understanding of how the disorder develops and may offer new pathways for treatment. Brain imaging studies were performed at the UCLA Brain Mapping Center.
FUNDING:
The study was funded by the National Institutes of Health (NIDDK and NCCAM).
AUTHORS:
The following authors are available to comment: Dr. Emeran Mayer, professor of medicine, David Geffen School of Medicine at UCLA; Dr. Douglas Drossman, professor of medicine, and Dr. Yehuda Ringel, lead study author and assistant professor of medicine, both at the University of North Carolina at Chapel Hill.
JOURNAL:
The research appears in the Feb. 1 online edition of the peer-reviewed journal Gastroenterology.
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Abuz de istorie regulament afecteazã durere la femeile cu sindromul intestinului iritabil - Abuse History Affects Pain Regulation In Women With Irritable Bowel Syndrome - articole medicale engleza - startsanatate