Adding Chemotherapy to Radiation May Improve Survival in Nasopharyngeal Cancer Patients
Nasopharyngeal cancer patients are usually treated with radiotherapy. Despite some encouraging early results, randomized trials in which chemotherapy was added before or after radiotherapy have not shown improvements in survival.
Anthony T. C. Chan, M.D., of the Prince of Wales Hospital in Hong Kong, and colleagues conducted a randomized trial in which 350 patients with locoregionally advanced nasopharyngeal carcinoma were treated with either radiotherapy alone or concurrently with cisplatin.
Overall 5-year survival was higher among patients treated with radiotherapy and cisplatin compared with radiotherapy alone (70.3% versus 58.6%, respectively). The authors conclude that these results confirm that the combination therapy has promise as a standard treatment in locoregionally advanced nasopharyngeal cancer.
Contact: Janet Chow, Chinese University of Hong Kong, (852) 2632 2846, janetchow@cuhk.edu.hk
Also in the April 6 JNCI:
• Sequence Variants in Toll-Like Receptor Gene Cluster (TLR6-TLR1-TLR10) and Prostate Cancer Risk
• Antioxidant May Have Adverse Effects in Head and Neck Cancer Patients:
eurekalert.org/emb_releases/2005-04/jotn-amh033105.php
• Studies Examine Menopausal Hormone Therapy and Risk of Breast Cancer Recurrence:
http://www.eurekalert.org/emb_releases/2005-04/jotn-sem033105.php
• Study Examines Effectiveness of Anti-Anemia Drug in Treatment of Cancer Patients:
http://www.eurekalert.org/emb_releases/2005-04/jotn-see033105.php
Note: The Journal of the National Cancer Institute is published by Oxford University Press and is not affiliated with the National Cancer Institute. Attribution to the Journal of the National Cancer Institute is requested in all news coverage. Visit the Journal online at http://jncicancerspectrum.oupjournals.org.
Contact: Sarah L. Zielinski
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
http://jncicancerspectrum.oupjournals.org
Adãugarea de Chimioterapie la radiaþii mai bunã de supravieþuire în Nasopharyngeal Rac Pacienþii - Adding Chemotherapy to Radiation May Improve Survival in Nasopharyngeal Cancer Patients - articole medicale engleza - startsanatate