Hijacking Of Neural Crest Genes
In this report, researchers in the laboratory of Dr. Marianne Bronner-Fraser at the California Institute of Technology have used the amphioxus genome sequence to investigate how this vertebrate-specific cell type evolved from an invertebrate ancestor.
The group found genes in amphioxus that are similar to vertebrate genes related to neural crest cells, however in cephalochordates they are used for other functions.
This finding raises the intriguing possibility that during vertebrate evolution, these genes may have "hijacked" for the development of neural crest cells.
Reference:
"Insights from the amphioxus genome on the origin of vertebrate neural crest."
Yu, J.-K., Meulemans, D., McKeown, S., and Bronner-Fraser, M.
Genome Res. doi:10.1101/gr.076208.108
About Genome Research
Genome Research is an international, monthly, peer-reviewed journal published by Cold Spring Harbor Laboratory Press. Launched in 1995, it is one of the five most highly cited primary research journals in genetics and genomics.
Genome Research
About Cold Spring Harbor Laboratory Press
Cold Spring Harbor Laboratory Press is an internationally renowned publisher of books, journals, and electronic media located on Long Island, New York. It is a division of Cold Spring Harbor Laboratory, an innovator in life science research and the education of scientists, students, and the public.
Cold Spring Harbor Laboratory Press
Deturnarea Din neurale Crest Genele - Hijacking Of Neural Crest Genes - articole medicale engleza - startsanatate