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Knee Pain? An Exclusive Study Engineers Cartilage To Match Patient's Own Tissue
Patients with knee cartilage
injuries now have the opportunity to re-grow their cartilage as part of an
innovative study at TRIA Orthopaedic Center, in Bloomington, MN. Cartilage
is the tough but flexible tissue that covers the ends of your bones at a
joint such as the knee; symptoms of knee cartilage defects include pain,
swelling and catching. In the United States alone, knee pain ranks the
second highest source of musculoskeletal-related physician visits in 2005,
according to the National Ambulatory Medical Care Survey. This new implant
technology, NeoCart(R), regenerates this injury-prone tissue within a
bio-engineered material, grown from the patient's own cartilage cells. The
matrix matches his or her unique cartilage characteristics, and is being
studied as an alternative to a standard therapy called microfracture. Dr.
Brad Nelson, Orthopaedic Surgeon and Principal Investigator for TRIA, will
be implanting this engineered tissue matrix for a select number of
patients.
Histogenics Corporation, makers of NeoCart(R), successfully completed
Phase I of the NeoCart(R) clinical trial, demonstrating the safety of the
technique in a small number of patients, and is now in Phase II, where
NeoCart(R) will be compared with a standard therapy called microfracture.
TRIA Orthopaedic Center is one of a limited number of sites in the country,
and the only site in Minnesota, chosen to participate in the study. "We are
thrilled to be one of five centers nationally participating in this
clinical trial," said Ryan Graver, Director of Research and education for
TRIA. "This kind of cutting-edge research improves Orthopaedic treatments
and outcomes that our patients can expect. Our commitment is to improve
care for all Orthopaedic patients and it is through such projects TRIA is
beginning to translate science into advancements in clinical care."
Since the body does not naturally re grow cartilage without medical
intervention the knee joints are prone to degeneration and osteoarthritis.
The NeoCart(R) implant, to replace the damaged cartilage, is cultured from
an initial biopsy where a pea size amount of a patient's healthy cartilage
is extracted. The biopsy sample is processed to pinpoint the cartilage
producing cells, then injected into a 3-D bioengineered matrix and placed
under high pressure to grow the cartilage. This matrix, with the same
characteristics of the patient's own cartilage, is then implanted to
replace the damaged cartilage. Patients participating in this study will
receive either NeoCart(R) or standard microfracture therapy.
TRIA has the potential to offer this research opportunity to 10 -15
patients. Patients between the ages of 18-55 with knee pain symptoms
indicative of an articular cartilage injury may be eligible to enroll in
the study. Patients in the study will have a MRI study and must be able to
undergo arthroscopic microfracture or biopsy and subsequent surgery for
NeoCart implantation.
There is no charge to the patient for the NeoCart implant used in this
study. The treatment cost of the patient's knee cartilage injury will
remain the same regardless of participation in the study, and is normally
covered under your medical/hospital insurance plan.
TRIA Orthopaedic Center is a state-of-the-science partnership of Park
Nicollet Health Services, University of Minnesota Physicians and The
Orthopaedic Center. This revolutionary facility delivers orthopaedic
treatment, surgery, rehabilitation, therapy, pharmacy, research and
physician education -- all under one roof. TRIA specialists train over 600
national and international surgeons on the latest techniques in orthopaedic
surgery in our Bio-Skills Laboratory. TRIA is conveniently located at
France Avenue and I- 494.
TRIA Orthopaedic Center
http://www.tria.com
Knee Pain? Exclusivitate Studiul Inginerilor cartilaj care sã se potriveascã cu proprii ale pacientului Tissue - Knee Pain? An Exclusive Study Engineers Cartilage To Match Patient's Own Tissue - articole medicale engleza - startsanatate