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Research Study Investigating New Post Heart Attack Treatment Has Begun Enrolling Patients

Northwestern University's Feinberg School of Medicine has received a $15 million grant from the National Heart, Lung and Blood Institute to conduct an international study investigating whether a pacemaker enabled administration of beta-blockers in patients with post-MI bradycardia or heart block will also improve survival rates.

Jeffrey Goldberger, M.D., professor of medicine at Feinberg and director of Cardiac Electrophysiology at Northwestern Memorial Hospital, is the national principal investigator of the multi-center, randomized clinical research study. The five-year study will enroll 1,124 patients from around the country, in Canada and in Israel.

"The study will also help us determine more precisely how frequently low heart rates are a problem in heart attack patients. The current estimates are 5 to 10 percent of 1.5 million heart attack patients yearly," Goldberger said.

Northwestern Memorial Hospital is the local site and will enroll 20 to 30 patients. Other centers are in 27 states, including Michigan, Minnesota, Iowa, Wisconsin and Missouri.

"This research question addresses a significant public health issue. As our population ages, we seek to address a question that could potentially improve post heart attack survival as well as improved the quality of life for heart attack patients. We have predicted and observed that the patient population for this study represents a group that is more elderly, with factors that influence eligibility and willingness to participate. The study should be offered for consideration to geriatric patients in order to gain knowledge about this treatment in elderly age group. Study oversight by an objective safety board assures ongoing review and monitoring for the safety of all study participants".

Goldberger noted most of the participants in the study will be patients identified in the hospital after a heart attack, allowing time to discuss the study with physicians, family and friends. The name of the study is the Pacemaker and Beta Blockers after Myocardial Infarction Trial (PACE-MI.) For more information, visit the website for the study at http://www.PACE-MI.org.

http://www.northwestern.edu





Studiu de cercetare de Investigare post nou atac de cord a început tratamentul, unde se pregãtesc de pacienþi - Research Study Investigating New Post Heart Attack Treatment Has Begun Enrolling Patients - articole medicale engleza - startsanatate