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Compares stomach acid control of three proton pump inhibitors in chronic NSAID users

Data from a clinical trial comparing stomach acid control of three proton pump inhibitors (PPIs), esomeprazole magnesium (NEXIUM®), lansoprazole (Prevacid), and pantoprazole (Protonix), in chronic users of non-steroidal anti-inflammatory drugs (NSAIDs) were presented today at the annual Digestive Disease Week® (DDW®). The analysis included users of traditional NSAIDs and selective COX-2 inhibitors.

The results of the multicenter, randomized, three-way, crossover study of 77 chronic users of COX-2 inhibitors or nonselective NSAIDs found that esomeprazole maintained a pH of greater than 4.0 for 17.8 hours (74.3 percent) of the 24-hour period while lansoprazole maintained it for 15.9 hours (66.4 percent, P=.0003)) and pantoprazole for 14.6 hours (60.7 percent, P





Comparã stomac acid de control de trei inhibitori de pompã de protoni în cronicã de AINS utilizatori - Compares stomach acid control of three proton pump inhibitors in chronic NSAID users - articole medicale engleza - startsanatate