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New Data Shows Veteran Drug Could Treat Cocaine Dependence
A recent pilot study conducted by
the Medical University of South Carolina (MUSC) supports the use of
mucus-dissolving agent /N/-acetylcysteine (NAC) for reducing an addict's
desire and interest in cocaine by increasing a chemical found in the brain.
Currently, there is no drug approved by the U.S. Food and Drug
Administration for the treatment of cocaine dependence. Study results
are comparable to existing data and animal models that confirm NAC as a
promising option. "Our team is very encouraged by these preliminary
positive findings," said Robert Malcolm, M.D., MUSC professor of
psychiatry and director of outpatient substance abuse programs. "We now
are working on a large outpatient treatment trial with N-acetylcysteine
and hope to have more information on effectiveness and safety in a 'real
world setting' within 12 to 18 months."
Cocaine-dependent participants were either given the NAC medication or a
placebo in the double-blind trial, which lasted during two separate,
three-day hospital stays. In addition to medication, participants were
shown slides depicting cocaine and its usage. Researchers lead by Steven
LaRowe, Ph.D., MUSC research assistant professor of psychiatry, then
gathered and recorded psychophysical data during their observations.
Those that were given the NAC drug reported less interest and desire in
using cocaine while responding to the visual stimulants, and even
watched the cocaine slides for a smaller amount of time.
About MUSC
Founded in 1824 in Charleston, The Medical University of South Carolina
is the oldest medical school in the South. Today, MUSC continues the
tradition of excellence in education, research, and patient care. MUSC
educates and trains more than 3,000 students and residents, and has
nearly 10,000 employees, including 1,300 faculty members. As the largest
non-federal employer in Charleston, the university and its affiliates
have collective annual budgets in excess of $1.3 billion. MUSC operates
a 600-bed medical center, which includes a nationally recognized
Children's Hospital and a leading Institute of Psychiatry. For more
information on academic information or clinical services, visit
http://www.musc.edu or http://www.muschealth.com.
Noile date aratã veteran de droguri ar putea trata dependenþa de cocainã - New Data Shows Veteran Drug Could Treat Cocaine Dependence - articole medicale engleza - startsanatate