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Vascular Endothelial Growth Factor Mediates Intracrine Survival In Human Breast Carcinoma Cells Through Internally Expressed VEGFR 1/FLT1
A study by Shalom Avraham and colleagues from the Beth Israel Deaconess Medical Center at the Harvard Institutes of Medicine provides evidence of a
survival system in breast cancer cells by which vascular endothelial growth factor, VEGF, acts as an internal autocrine survival factor through
binding to its receptor, VEGFR1.
Citation: Lee TH, Seng S, Sekine M, Hinton C, Fu Y, et al. (2007)
Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1.
PLoS Med 4(6): e186.
Link here
About PLoS Medicine
PLoS Medicine is an open access, freely available international medical journal. It publishes original research that enhances our understanding of
human health and disease, together with commentary and analysis of important global health issues. For more information, visit
www.plosmedicine.org
About the Public Library of Science
The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world's scientific and medical
literature a freely available public resource. For more information, visit www.plos.org
Factor de creºtere a endoteliului vascular mediazã Intracrine de supravieþuire în carcinom de sân umane intern, exprimate prin celule VEGFR 1/FLT1 - Vascular Endothelial Growth Factor Mediates Intracrine Survival In Human Breast Carcinoma Cells Through Internally Expressed VEGFR 1/FLT1 - articole medicale engleza - startsanatate